The initial idioms of the letter U

up one’s alley	up one side and down the other
up one's alley	up (one's) street
up pot	up shit creek
up shit creek without a paddle	up shit's creek (without a paddle)
up sleeve	up stakes
up sticks	up the ante
up the creek	up the creek without a paddle
up the duff	up the pole
up the river	up the spout
up the stick	up the wall
up the walls	up the wazoo
up the wind	up the yin-yang
up there	up there with
up time	up to (one's) eyeballs (in something)
up to ninety	up to a point