1. n. a try at something. Go ahead. Give it another shot.
2. mod. exhausted; ruined. Here’s your pen back. It’s shot anyway.
3. n. a rocket launching. The shot was canceled because of the weather.
4. n. a small or quickly drunk drink of liquor, usually whiskey. He stopped at every bar on the strip for a quick shot.
5. n. an injection of drugs. Just one shot of that stuff and you’re hooked for life.
6. mod. alcohol intoxicated. They are a little noisy, I guess, but after all they are shot—you know, plastered.