1. n. a tobacco cigarette; a pipe of tobacco; a cigar. I think I’ll have a smoke now.
2. n. the act of smoking anything smokable, including drugs. I need a smoke—of anything. I’m going to stop here for a smoke.
3. n. methyl alcohol; bad liquor; any liquor. They call it smoke because when you mix it with water and shake it, it’s cloudy.
5. tv. to annihilate someone; to shoot someone. (Underworld.) Rocko tried time and time again to smoke Marlowe, always without success.
6. tv. to beat someone in a contest; to outrun, outdistance, or outplay someone. Jill smoked Dave in the bicycle race.