| Sacnite | | - | Native American, Mayan | |
| Saqui | | - | Native American, Mapuche | |
| Sayen | | - | Native American, Mapuche | |
| Shanice | | shə-NEES | African American (Modern) | |
| Shanika | | shə-NEE-kə | African American (Modern) | |
| Shaniqua | | shə-NEE-kwə | African American (Modern) | |
| Shelena | | - | African American (Rare) | |
| Shikoba | | - | Native American, Choctaw | |
| Sissinnguaq | | - | Native American, Greenlandic | |
| Tajuana | | - | African American (Rare) | |
| Talisha | | tə-LEESH-ə, tə-LISH-ə | African American (Rare) | |
| Tamaya | | - | Native American, Quechua | |
| Taneka | | tə-NEE-kə | African American (Rare) | |
| Tanesha | | tə-NEE-shə | African American | |
| Tanika | | tə-NEE-kə | African American | |