| SÉRgio | | SER-zhyoo | Portuguese | |
| SÍLvia | | - | Portuguese, Catalan | |
| Sabina | | sah-BEE-nah (Italian, Spanish, Polish) | Italian, Spanish, Portuguese, Romanian, Polish, Czech, Slovene, Russian, Croatian, Ancient Roman | |
| SalomÃO | | - | Portuguese | |
| SalomÉ | | sə-loo-ME (Portuguese) | French, Spanish, Portuguese | |
| Samuel | | SAM-yoo-əl (English), SAM-yəl (English), sah-MWEL (Spanish), SAH-moo-el (Swedish, Finnish) | English, French, German, Dutch, Spanish, Portuguese, Polish, Czech, Slovak, Swedish, Norwegian, Dani | |
| Sandra | | SAHN-drah (Italian, Dutch, Finnish), SAN-drə (English), ZAHN-drah (German) | Italian, English, French, Spanish, Portuguese, German, Dutch, Swedish, Norwegian, Danish, Icelandic, | |
| Santiago | | sahn-TYAH-go (Spanish) | Spanish, Portuguese | |
| Sara | | SAH-rah (Spanish, Finnish, Dutch, Polish), ZAH-rah (German), SER-ə (English), SAR-ə (English), SAH:-rah (Arabic) | Greek, Spanish, Italian, Portuguese, Catalan, Swedish, Norwegian, Danish, Icelandic, Finnish, German | |
| Saturnino | | sah-toor-NEE-no (Spanish, Italian) | Spanish, Italian, Portuguese | |
| SebastiÃO | | - | Portuguese | |
| Serafina | | se-rah-FEE-nah (Polish) | Italian, Portuguese, Spanish, Polish | |
| Severina | | - | Italian, Portuguese, Croatian, German, Ancient Roman | |
| Severino | | se-ve-REE-no (Italian, Spanish) | Italian, Spanish, Portuguese | |
| Silvestre | | seel-BE-stre (Spanish) | Spanish, Portuguese | |