| Sergiu | | - | Romanian | |
| Sergius | | - | Ancient Roman | |
| Servatius | | - | Late Roman | |
| Servius | | SER-wi-uws | Ancient Roman | |
| Severianus | | - | Ancient Roman | |
| Severina | | - | Italian, Portuguese, Croatian, German, Ancient Roman | |
| Severinus | | - | Ancient Roman | |
| Severus | | - | Ancient Roman | |
| Sextilius | | - | Ancient Roman | |
| Sextus | | SEKS-tuws | Ancient Roman | |
| Sibylla | | zi-BUY-lah (German) | Greek, German, Swedish, Late Roman, Late Greek | |
| Sidonia | | - | Late Roman, German | |
| Sidonius | | - | Late Roman | |
| Silvanus | | sil-VAY-nəs (English) | Roman Mythology, Ancient Roman, Biblical, Biblical Latin | |
| Silvester | | sil-VES-tər (English) | Dutch, English, Slovene, Slovak, German, Late Roman | |